Single nucleotide polymorphism (SNP) discovery and linkage mapping of bovine cytokine genes
نویسندگان
چکیده
منابع مشابه
Single nucleotide polymorphism (SNP) discovery in porcine expressed genes.
High-throughput genotyping of swine populations is a potentially efficient method for establishing animal lineage and identification of loci important to animal health and efficient pork production. Markers were developed based upon single nucleotide polymorphisms (SNPs), which are abundant and amenable to automated genotyping platforms. The focus of this research was SNP discovery in expressed...
متن کاملLinkage mapping of a single nucleotide polymorphism (SNP) in the porcine QDPR gene to chromosome 8.
Source ⁄ description of primers: Quinoid dihydropteridine reductase (QDPR) catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin and is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. A cDNA clone containing the full coding region of the porcine QDPR (GenBank accession no. AF526879) has been isolated from the Meat Animal Research Center (M...
متن کاملPublication of stand-alone single nucleotide polymorphism (SNP) discovery data.
In the recent past, several publications have appeared in Drug Metabolism and Disposition that described the results of single nucleotide polymorphism (SNP) discovery projects. The publications were limited to only this aspect of the science and failed to include any studies that extended beyond the discovery phase. No attempt was made to elucidate the possible functional significance of the id...
متن کاملSingle Nucleotide Polymorphism Analysis of Protamine Genes in Infertile Men
Background Single nucleotide polymorphism (SNPs) are considered as one of the underlying causes of male infertility. Proper sperm chromatin packaging which involves replacement of histones with protamines has profound effect on male fertility. Over 20 SNPs have been reported for the protamine 1 and 2. MaterialsAndMethods The aim of this study was to evaluate the frequency of two previously repo...
متن کاملSingle-nucleotide polymorphism mapping.
Single-nucleotide polymorphism (SNP) mapping is the easiest and most reliable way to map genes in Caenorhabditis elegans. SNPs are extremely dense and usually have no associated phenotype, making them ideal markers for mapping. SNP mapping has three steps. First, recombinant mutant animals are generated over a polymorphic strain (usually CB4856) using standard genetic techniques. Second, the ge...
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ژورنال
عنوان ژورنال: Mammalian Genome
سال: 1999
ISSN: 0938-8990,1432-1777
DOI: 10.1007/s003359901162